Excerpt from Observations on the Direct Influence of Variations of Arterial Pressure Upon the Rate of Beat of the Mammalian Heart The higher aortic pressure is, the more force must be expended by the left ventricle in forcing open the semilunar valves; that is to say, the higher will be intraventricular systolic pressure. It is this inﬂuence only of increased aortic pressure which should be meant ...
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